Great Plains Lab Organic Acids Test (OAT)

The Organic Acids Test (OAT) offers a comprehensive metabolic snapshot of a patient’s overall health with over 70 markers.  It provides an accurate evaluation of intestinal yeast and bacteria. Abnormally high levels of these microorganisms can cause or worsen behavior disorders, hyperactivity, movement disorders, fatigue and immune function. Many people with chronic illnesses and neurological disorders often excrete several abnormal organic acids in their urine. The cause of these high levels could include oral antibiotic use, high sugar diets, immune deficiencies, acquired infections, as well as genetic factors.

Great Plains Laboratory’s Organic Acids Test also includes markers for vitamin and mineral levels, oxidative stress, neurotransmitter levels, and is the only OAT to include markers for oxalates, which are highly correlated with many chronic illnesses.

If abnormalities are detected using the OAT, protocol can include supplements, such as vitamins and antioxidants, or dietary modification. Following protocol, patients and practitioners have reported significant improvement such as decreased fatigue, regular bowel function, increased energy and alertness, increased concentration, improved verbal skills, less hyperactivity, and decreased abdominal pain.


Organic Acid Test is recommended for individuals with the following disorders:

  • Depression

  • Anxiety

  • Insomnia

  • ADHD/ADD

  • Autism

  • Inflammatory Disorders

  • GI Dysfunction

  • Yeast Overgrowth

  • Mold Colonization

  • Mitochondrial Dysfunction

  • Neurotransmitter Imbalance

  • Detoxification Disorders

  • Kidney Stones/Oxalate Related Conditions


Please note that the OAT Test can be selected individually or as part of the Enviro-TOX Panel, which also includes the GPL-TOX Profile and Glyphosate Test.